Objective To construct the evaluation index system of core competence for organ transplant specialist nurses.Methods The first draft of evaluation index system was drawn up by referring to domestic and foreign literature,expert interviews and research group discussion. Totally 25 experts in China were consulted twice by Delphi method,and the weight of indexes at all levels was determined by analytic hierarchy process（AHP）.Results The positive coefficients and authority coefficients for 2 rounds of consultation were 100% and 0.836. The coordination coefficient of expert opinions in the first,second and third level indexes were 0.404,0.449,and 0.308（P<0.001）. The final evaluation index system of core competence of organ transplant specialist nurses included 7 first-level indexes（Theoretical Knowledge,Professional Skills,Critical Thinking Ability,Interpersonal Skills,Management Ability,Psychological Traits,and Specialty Development Ability）,22 second-level indexes and 58 third-level indexes.Conclusion The evaluation index of core competence of organ transplant specialist nurses is logical and reliable,which can be used as reference for training organ transplant nurses.